The best time to control weeds in asparagus is early spring before the asparagus emerges. A light tilling (or hoeing) that is shallow enough to avoid the crowns will eliminate existing weeds. Many gardeners like to mix in organic matter during the same operation.
Herbicides can be used before asparagus emerges. Glyphosate (Roundup, Killzall) will kill weeds that are actively growing, and the preemergence herbicide trifluralin can be used to kill weed seeds as they germinate. Trifluralin is found in several products, but not all of them list asparagus on the label. Those that do have asparagus on the label include Miracle-Gro Weed Preventer Granules and Monterey Vegetable and Ornamental Weeder. Mulch can also be used to keep weeds from invading.
No herbicides can be used during harvest. The end of harvest presents another opportunity. Remove all fern and spears and apply Roundup to control virtually all of the weeds present. Past the harvest season and after regrowth of the asparagus, options are limited. Products that contain sethoxydim can be applied to asparagus to kill grassy weeds. Sethoxydim has no effect on broadleaves including asparagus. Two sethoxydim products available to homeowners and
labeled for asparagus are Monterey Grass Getter and Hi-Yield Grass Killer. With broadleaves, the only option is to pull them and look forward to next year. (Ward Upham)